Frontal Cortex Neuropathology in Dementia Pugilistica
نویسندگان
چکیده
منابع مشابه
Dementia pugilistica
Historical note and nomenclature Boxing has been a human activity since antiquity (Corsellis 1989). The safety of boxers became an issue in the early 19th century when the use of spikes and other brutal methods was outlawed in Great Britain. In 1866 the Marques of Queensbury Rules established the use of boxing gloves, weight categories, and the 10-second knockout. However, these measures did no...
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Extensive exposure of boxers to neurotrauma in the early 20th century led to the so-called punch drunk syndrome, which was formally recognized in the medical literature in 1928. "Punch drunk" terminology was replaced by the less derisive 'dementia pugilistica' in 1937. In the early case material, the diagnosis of dementia pugilistica required neurological deficits, including slurring dysarthri...
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Brains from 12 patients dying with a clinical diagnosis of frontal lobe dementia have been examined at post mortem. In pathological terms four groups were encountered. Groups A and B showed severe frontal and temporal lobe atrophy characterised histologically in group A by severe neuronal loss, spongiform change of the superficial laminae, and mild astrocytosis; in group B severe neuronal loss ...
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Frontotemporal dementia (FTD) is a clinical phenotype of dementia, characterized by complex of clinical symptoms, including disinhibition, character change, increased appetite, sexual misconduct and language problems. Frontotemporal lobar degeneration (FTLD) is a pathological classification of neurodegenerative disorder and its core consists of Pick's disease (PiD). Historically, PiD was morpho...
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Dementia, being not a specific disease but a syndrome characterized by deficits in several cognitive domains, is a major public health and socio-economic problem of our century. It is caused by dysfunction/loss of synapses and neurons inducing default neuronal networks. Despite updated concensus criteria for the clinical diagnosis of the major neurodegenerative disorders and new biomarkers, the...
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ژورنال
عنوان ژورنال: Journal of Neurotrauma
سال: 2012
ISSN: 0897-7151,1557-9042
DOI: 10.1089/neu.2011.1957